Exercise, such as walking, triggers the release of osteocalcin which interacts with key proteins in the brain to boost memory. The findings provide an evidence that exercise may be the best way to stave off or even treat, age-related memory loss in people.
Researchers have identified a naturally occurring bone hormone that can potentially reverse memory loss in the ageing brain through exercise. The study on the hormone osteocalcin lends new insight into how lifestyle changes that affect the body, such as exercise, could positively affect the brain.
"Nearly everyone will experience age-related memory loss in their lifetime, so it is incredibly important to understand its causes and identify ways to mitigate it," said Eric R. Kandel, Professor at the Columbia University. "With today′s study, we are not only building a detailed understanding of how age-related memory loss originates in the brain, we′ve shown how osteocalcin interacts with key proteins in the brain to boost memory."
For many years, memory loss was treated as a singular disorder. But scientists have now begun to realise that Alzheimer′s disease, begins in a part of the brain called the entorhinal cortex, which lies at the foot of the hippocampus. On the other hand, age-related memory loss, begins within the hippocampus itself, in a region called the dentate gyrus, Kandel said.
Kandel′s team identified a deficiency in a protein called RbAp48 protein, a significant contributor to age-related memory loss but not Alzheimer′s. The protein levels decline with age, both in mice and in people. In a series of experiments, reported in the journal Cell Reports, the team found that RbAp48 controls the expression levels of two other proteins regulated from osteocalcin.
If RbAp48 function is inhibited, osteocalcin infusions have no effect on the animals′ memory. Osteocalcin needs RbAp48 to kick start the process. These findings also provide further evidence that exercise may be the best way to stave off or even treat, age-related memory loss in people. Studies in mice showed that moderate exercise, such as walking, triggers the release of osteocalcin in the body.
Related News
Hard work, no pay linked to mental health issues in comedians
The best effective and natural plants for a good memory
Heres why you should go sulphate-free with your hair care
5 Yoga Poses that Can Give You a Glowing Skin
Skin tone linked to fruit and vegetable consumption
23 foods that contain NO calories
Grean tea could help get rid of acne
Eat more fruit and veg for a longer life
Most Read
★Is This the Best Diet for Post-Menopausal Women?
★5 superfoods to combat hair loss
★Whole-body vibration may be as effective as regular exercise
★This One Exercise Helps You Become a Better Runner
★Grean tea could help get rid of acne
★Cancer risk of breast implants 10 times higher than first feared
★Haryana girl Nishtha Dudeja wins Miss Deaf Asia 2018 crown
★Everyday Medications You Should Never Take When You Exercise
★10 Healthy Twists on Classic Diner Dishes
★Healthiest Foods For Women
★How to Gain Weight in 7 Days to Get Rid of the Skinny You
★12 Benefits of Hair Spa Treatment
★Can high heels give you cancer?
★A Beginners Guide to Sun Salutations
★15 Powerful Asanas of Yoga to Reduce Belly Fat
★Aerobic training can help reverse ageing
★9 Food Habits To Keep Eating To Lose Weight
★Does ginger gene offer key to younger looking skin?
★Study reveals alarming dangers of anti-ageing jabs
★Cooking in aluminium pans may be dangerous for your health
★10 Surprising Things That Can Cause You to Lose Muscle
★Dandelion Benefits Biodiversity, Soil and Your Health
★3 Must Try Face Yoga Exercises For Glowing Face
★This is how many calories your tea and coffee habit is adding to your diet EVERY DAY
★7 Must-Eat Fermented Foods for a Healthy Gut
★Red Heart Tea Recipe
★6 Best Oils for a Naturally Clear and Glowing Skin
★The Best Breakfast Foods for Weight Loss
★5 DIY masks for your various hair concerns
★5 Hot Yoga Poses For Rapid Weight Loss
★Top 10 Homemade Fruit Packs for Glowing Skin
★Vitamin reverses aging in organs and muscles
★Plum goodness for your hair!
★5 Dairy-Free Cheese Options Worth Trying
★Just ten minutes of play a day can help children reduce their risk of developing heart disease and diabetes later in life
★The Brilliant Food Combo That Helps You Burn More Fat
★8 Fruits that Burn Fat: Include Them In Your Diet For Great Health Benefits
★Popular weight loss strategies
★10 Most Effective Weight Loss Exercises For Torching Fat
★5 Common Mistakes that May Ruin Your Skin
★12 Real Amazing Benefits Of Skipping For Weight Loss
★Recycling temple waste along the Ganges with Help Us Green
★Exercise can help boost memory through bone hormone: Study
★6 Best Oils for a Naturally Clear and Glowing Skin
★Pasta eaters may have better diet quality: study
★9 Super Simple Exercises to Reduce Belly Fat
★Scientists found effective dandruff treatment
★The best effective and natural plants for a good memory
★How to Lose Weight Fast: 3 Simple Steps, Based on Science
★Hair removal injuries rocketed NINE-FOLD since 1991