Exercise can help boost memory through bone hormone: Study

Exercise, such as walking, triggers the release of osteocalcin which interacts with key proteins in the brain to boost memory. The findings provide an evidence that exercise may be the best way to stave off or even treat, age-related memory loss in people.

Researchers have identified a naturally occurring bone hormone that can potentially reverse memory loss in the ageing brain through exercise. The study on the hormone osteocalcin lends new insight into how lifestyle changes that affect the body, such as exercise, could positively affect the brain.

"Nearly everyone will experience age-related memory loss in their lifetime, so it is incredibly important to understand its causes and identify ways to mitigate it," said Eric R. Kandel, Professor at the Columbia University. "With today′s study, we are not only building a detailed understanding of how age-related memory loss originates in the brain, we′ve shown how osteocalcin interacts with key proteins in the brain to boost memory."

For many years, memory loss was treated as a singular disorder. But scientists have now begun to realise that Alzheimer′s disease, begins in a part of the brain called the entorhinal cortex, which lies at the foot of the hippocampus. On the other hand, age-related memory loss, begins within the hippocampus itself, in a region called the dentate gyrus, Kandel said.

Kandel′s team identified a deficiency in a protein called RbAp48 protein, a significant contributor to age-related memory loss but not Alzheimer′s. The protein levels decline with age, both in mice and in people. In a series of experiments, reported in the journal Cell Reports, the team found that RbAp48 controls the expression levels of two other proteins regulated from osteocalcin.

If RbAp48 function is inhibited, osteocalcin infusions have no effect on the animals′ memory. Osteocalcin needs RbAp48 to kick start the process. These findings also provide further evidence that exercise may be the best way to stave off or even treat, age-related memory loss in people. Studies in mice showed that moderate exercise, such as walking, triggers the release of osteocalcin in the body.

Most Read

★Top 10 Unknown Beauty Tips and Tricks

★Vitamin reverses aging in organs and muscles

★Work stress may lead to irregular heart rate

★Grean tea could help get rid of acne

★Using Kalonji Seeds for Weight Loss

★Why You Probably Shouldnt Take Diet Advice from Your CrossFit Coach

★Take care of your coloured hair with Wella

★8 Time-Saving Meal Prep Ideas Nutritionists Actually Use

★5 Skincare resolutions for 2019 that you must keep

★Plum goodness for your hair!

★A platter full of seafood

★Losing Weight in Hot Weather Made Easy

★8 Fruits that Burn Fat: Include Them In Your Diet For Great Health Benefits

★4 Superfoods for a Healthy Looking Skin

★9 Simple Yoga Asanas & Tips for Weight Loss

★5 Hot Yoga Poses For Rapid Weight Loss

★Research reveals surprising health benefits of chewing your food

★Haryana girl Nishtha Dudeja wins Miss Deaf Asia 2018 crown

★The Key to Healthy Aging

★Smoking and sight loss warning

★5 most surprising cosmetic surgery trends across the globe

★4 Totally avoidable gym mistakes

★How you should wash your face?

★Can Eating Bananas Help You Lose Weight?

★8 Practical Tips to Lose Weight Without Dieting

★Teenagers use social media posts to appear attractive to friends

★Growing Propagating and Using Aloe Vera

★7 Filling Foods to Keep Belly Fat at Bay

★How to exercise outdoors, when the smogs a killer

★5 superfoods to combat hair loss

★Top 10 Fruits To Eat To Lose Weight Quickly

★Guinness World Record for bearded woman Harnaam Kaur

★Mushrooms could prevent risk of Dementia, scientists say

★9 Super Simple Exercises to Reduce Belly Fat

★The amazing and healthy benefits of meditation!

★Dandelion Benefits Biodiversity, Soil and Your Health

★Try these 4 simple yoga asanas to gain weight

★Looking towards India for design

★The Beauty Benefits of Exercise

★Numerous health benefits of bitter melon (uses , side effects)

★Carbohydrates and sugars

★This is how many calories your tea and coffee habit is adding to your diet EVERY DAY

★Daylight Savings Time: That miserable time of year when many mourn loss of one-hour sleep

★Yoga Asanas To Prevent Hair Loss

★How to Lose Weight Fast: 3 Simple Steps, Based on Science

★Learn to Do Vinyasa Yoga for Weight Loss

★Can high heels give you cancer?

★Know why milk should be a part of your beauty regimen

★6 Foods You Can Incorporate In Your Fat Burner Diet For Best Results

★6 Fantastic Yoga Asanas That Will Help You Fight Skin Problems


©2025 All rights reserved. shapesnfitness.com